Universitą degli studi di Pavia
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Tematiche di Ricerca
Research topics currently active for the PhD students in Genetics, Molecular and Cellular Biology. The names of supervisors who can host PhD students are in parentheses. Additional information can be found in the page of each supervisor.
- Genomics, archaeogenomics and phylogeography of human populations and animal species (mainly livestock and others closely interacting with humans) (A. Achilli, L. Ferretti, A. Olivieri, O. Semino, A. Torroni)
- Ancient DNA assessment of museum and historical specimens (A. Achilli, A. Olivieri).
- Molecular biology, cytogenetics, epigenomics for the study of mammalian centromeres and telomeres and of their involvement in evolution and carcinogenesis (E. Giulotto, S. Nergadze, E. Raimondi).
- Genome instability mechanisms: identification and functional characterization of markers relevant for tumor development and progression (O. Cazzalini, G.N. Ranzani P. Perucca, E. Prosperi, S. Sabbioneda, L. A. Stivala).
- Alternative splicing regulation in developmental processes and diseases (G. Biamonti, C. Ghigna).
- Cross-talk between DNA and RNA metabolism in response to different stress stimuli, in cancer and neurodegeneration (G. Biamonti, C. Ghigna, S. Francia, G, Liberi, A. Montecucco).
- Bioinformatics approaches for the genomic and functional characterization of long non-coding RNAs (S. Bione).
- Study of hereditary disorders using molecular and bioinformatics approaches (G. Biino, E. Botta, D. Orioli, F. Peverali, E. Prosperi, G. N. Ranzani, S. Sabbioneda).
- Genomics and epigenomics in the study of neurodegenerative disorders in adults and children (C. Cereda).
- The autophagy process in celiac disease (S. Comincini).
- Viral oncogenesis and the role of T-cell response in controlling the development of virus-associated tumors (F. Baldanti).
- Cellular and molecular studies of the effects induced by platinum compounds and metabolic diseases on the development of the central nervous system (M.G. Bottone).
- Cellular and molecular mechanisms underlying gamete maturation and pluripotent cell differentiation (V. Merico).
- Cytochemical and ultrastructural studies of the nuclear processes of transcript maturation and of the influence of epigenetic modifications (M. Biggiogera).
- Cyto-histochemical studies of normal and pathological tissues and organs, and in experimental conditions (V. Bertone).
- Fluorescence analysis as a tool for investigating biological processes (A.C. Croce).
- Mechanisms of action of candidate molecules (natural or synthetic) for the prevention and therapy of human diseases (M. Savio, L. A. Stivala).
- Gene cloning, functional characterization and molecular mechanisms of enzymes, antibodies and proteins, potential targets of pharmacological drugs. Development of new antiviral and anticancer drugs, determination of the mechanism of activity and resistance (F. Focher, G. Maga).
- Search for new drugs and novel combination regimens against Mycobacterium tuberculosis and non-tuberculous mycobacteria (M.R. Pasca).
- Development of new treatments against the cystic fibrosis pathogen Burkholderia cenocepacia (G. Barbieri, S. Buroni).
- Studies on human monoamine oxidases and their role in oxidative stress; structural biology of enzymes relevant for industrial biocatalytic applications (C. Binda).
- Microbial biotechnologies for production of industrially-relevant molecules (C. Calvio).
- Regulation of virulence and metabolism in Streptococcus agalactiae (G. Barbieri, S. Buroni).
- Phenotypic and molecular characterization of multi drug resistant (MDR) bacterial pathogens: hospital and environmental epidemiology (R. Migliavacca).
- Genomics and bioinformatics for the study of interactions, from mutualistic symbiosis to pathogenic infections (D. Sassera).
- Functional and population genomics of harmful insects for tracking the invasion processes and for the development of control methods; studies on mosquito immunity and vector competence (M. Bonizzoni, L.M. Gomulski, L. Ometto).
- DNA damage response in the context of seed germination (A. Balestrazzi).
- Involvement of miRNAs in the regulation of DNA damage response in plants (A. Macovei).
- Improving photosynthesis and crop productivity by modulating photoprotective mechanisms (A. Pinnola).
