Universitą degli studi di Pavia
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Bonomi's CV
Serena Bonomi. Place and date of birth: Lovere (BG), 03/05/1984. Citizenship: Italian.
Address: Via Don Bassi 5 - 25052 Piancogno (BS) - Italy.
Work address: Institute of Molecular Genetics of the Italian National Research Council (IGM-CNR) – Via Abbiategrasso 207 - 27100 Pavia - Italy. Phone number: ++39/0382/546375
E-mail: bonomi@igm.cnr.it
Formal Education
2009 – present PhD Program in Genetic and Biomolecular Science under the supervision of Dr. Claudia Ghigna (CNR Researcher). University of Pavia, Pavia - Italy.
2007 – 2009 Full marks and honors (110/110, cum laude) in Experimental and Applied Biology. University of Pavia, Pavia - Italy. Research thesis with experimental work on alternative splicing.
2004 – 2007 Full marks and honors (110/110, cum laude) in Biotechnology (first level degree). University of Pavia, Pavia - Italy. Research thesis with experimental work on alternative splicing.
Research experience
Sept 2009 – present PhD in Genetic and Biomolecular Science of the University of Pavia, at the IGM-CNR, in the Molecular and Cellular Biology of the Nucleus Section directed by Dr. Giuseppe Biamonti, under the supervision of Dr. Claudia Ghigna. My primary research interest is to investigate and characterize the pathways regulating alternative splicing that become deregulated in cancer. To this aim I use as an experimental model the Ron proto-oncogene, a tyrosine kinase receptor that controls processes occurring during the epithelial-to-mesenchymal transition, a cellular program involved in cancers progression and metastasis formation. During this period, I contributed also in investigating how the cancer-specific ΔRon splicing isoform could be used as a target for new potential anti-metastatic therapies.
Sept 2007 – Jul 2009 Second Level Graduation Thesis at the IGM-CNR under the supervision of Dr. Claudia Ghigna. My main aim was to define the molecular mechanism and the splicing factors regulating the Ron proto-oncogene alternative splicing. In this period, I contributed to the identification of signaling pathways regulating the expression level of SRSF1, the splicing factor and proto-oncogene that controls Ron splicing during the epithelial-to-mesenchymal transition.
Sept 2006 – Jul 2007 First Level Graduation Thesis at the IGM-CNR under the supervision of Dr. Claudia Ghigna. My specific aim was to identify cis- and trans-acting elements involved in the regulation of alternative splicing of the Ron proto-oncogene.
Additional Education and Research experiences
AY 2011 – 2012 Tutoring collaboration in a project of the University of Pavia for the “Genetics course”. My roles as tutor are preparation and executions of exercises, support to students during the didactic activity.
AY 2008 – 2009 Tutoring collaboration in a project of the University of Pavia for the “Didactic laboratory of Molecular Biology”. My roles as tutor have been preparation of material for experiments, organization, achievement and support to students during the didactic activity.
Feb 2008 Practical course EURASNET “Workshop on Alternative Splicing and Disease”. University of Montpellier 2, Montpellier - France. February 18-23, 2008.
I have had the opportunity to be part of a small group of 26 students selected to attend this practical hands-on workshop, that covered a variety of techniques and tools for the study of alternative splicing related to human disease.
Awards and fellowships
26 june – 2 july 2011 Selected, with others 6 Italian young researchers for a total of 570 students from around the world, to attend the “61st Lindau Nobel Laureate Meeting”. Lindau – Germany.
Jan 2011 – dec 2011 Graduate student fellowship for the project “Role of alternative splicing in tumor progression”, in Dr. Giuseppe Biamonti laboratory, financed by “Fondazione Cariplo”.
Jan 2010 – dec 2010 Graduate student fellowship for the project “Role of alternative splicing in tumor progression”, in Dr. Giuseppe Biamonti laboratory, financed by “Fondazione Cariplo”.
AY 2009 – 2010 “Fondazione MINTAS” fellowship for neo-graduate students, alumnus of the “Collegio S. Caterina da Siena” of Pavia*, consisting in room and board free of charge, in the college, for one academic year, for (post) graduate studies.
AY 2005 – 2009 Selected as alumnus of the “Collegio S. Caterina da Siena” of Pavia*.
* “historic” college of Pavia and one of the thirteen Italian university institutions of high cultural qualification set under the control of the Ministry of Education, Universities and Research (MIUR).
Congresses Participation
61st Lindau Nobel Laureate Meeting”. Landau – Germany. 26 june - 2 july 2011.
DGM-IGM Conference. Pavia – Italy. 22-23 February 2011.
“CNR and the New Biology” Conference of the Department of Life Sciences, CNR. Rome - Italy. October 11-12, 2010.
IV Annual EURASNET Meeting. Assisi - Italy. April 23-24, 2009.
EURASNET Interdisciplinary Focus Meeting “Mouse model for alternative splicing”. Assisi - Italy. April 22, 2009.
10th FISV Annual Congress (FISV 2008). Riva del Garda - Italy. September 24-27, 2008.
Address: Via Don Bassi 5 - 25052 Piancogno (BS) - Italy.
Work address: Institute of Molecular Genetics of the Italian National Research Council (IGM-CNR) – Via Abbiategrasso 207 - 27100 Pavia - Italy. Phone number: ++39/0382/546375
E-mail: bonomi@igm.cnr.it
Formal Education
2009 – present PhD Program in Genetic and Biomolecular Science under the supervision of Dr. Claudia Ghigna (CNR Researcher). University of Pavia, Pavia - Italy.
2007 – 2009 Full marks and honors (110/110, cum laude) in Experimental and Applied Biology. University of Pavia, Pavia - Italy. Research thesis with experimental work on alternative splicing.
2004 – 2007 Full marks and honors (110/110, cum laude) in Biotechnology (first level degree). University of Pavia, Pavia - Italy. Research thesis with experimental work on alternative splicing.
Research experience
Sept 2009 – present PhD in Genetic and Biomolecular Science of the University of Pavia, at the IGM-CNR, in the Molecular and Cellular Biology of the Nucleus Section directed by Dr. Giuseppe Biamonti, under the supervision of Dr. Claudia Ghigna. My primary research interest is to investigate and characterize the pathways regulating alternative splicing that become deregulated in cancer. To this aim I use as an experimental model the Ron proto-oncogene, a tyrosine kinase receptor that controls processes occurring during the epithelial-to-mesenchymal transition, a cellular program involved in cancers progression and metastasis formation. During this period, I contributed also in investigating how the cancer-specific ΔRon splicing isoform could be used as a target for new potential anti-metastatic therapies.
Sept 2007 – Jul 2009 Second Level Graduation Thesis at the IGM-CNR under the supervision of Dr. Claudia Ghigna. My main aim was to define the molecular mechanism and the splicing factors regulating the Ron proto-oncogene alternative splicing. In this period, I contributed to the identification of signaling pathways regulating the expression level of SRSF1, the splicing factor and proto-oncogene that controls Ron splicing during the epithelial-to-mesenchymal transition.
Sept 2006 – Jul 2007 First Level Graduation Thesis at the IGM-CNR under the supervision of Dr. Claudia Ghigna. My specific aim was to identify cis- and trans-acting elements involved in the regulation of alternative splicing of the Ron proto-oncogene.
Additional Education and Research experiences
AY 2011 – 2012 Tutoring collaboration in a project of the University of Pavia for the “Genetics course”. My roles as tutor are preparation and executions of exercises, support to students during the didactic activity.
AY 2008 – 2009 Tutoring collaboration in a project of the University of Pavia for the “Didactic laboratory of Molecular Biology”. My roles as tutor have been preparation of material for experiments, organization, achievement and support to students during the didactic activity.
Feb 2008 Practical course EURASNET “Workshop on Alternative Splicing and Disease”. University of Montpellier 2, Montpellier - France. February 18-23, 2008.
I have had the opportunity to be part of a small group of 26 students selected to attend this practical hands-on workshop, that covered a variety of techniques and tools for the study of alternative splicing related to human disease.
Awards and fellowships
26 june – 2 july 2011 Selected, with others 6 Italian young researchers for a total of 570 students from around the world, to attend the “61st Lindau Nobel Laureate Meeting”. Lindau – Germany.
Jan 2011 – dec 2011 Graduate student fellowship for the project “Role of alternative splicing in tumor progression”, in Dr. Giuseppe Biamonti laboratory, financed by “Fondazione Cariplo”.
Jan 2010 – dec 2010 Graduate student fellowship for the project “Role of alternative splicing in tumor progression”, in Dr. Giuseppe Biamonti laboratory, financed by “Fondazione Cariplo”.
AY 2009 – 2010 “Fondazione MINTAS” fellowship for neo-graduate students, alumnus of the “Collegio S. Caterina da Siena” of Pavia*, consisting in room and board free of charge, in the college, for one academic year, for (post) graduate studies.
AY 2005 – 2009 Selected as alumnus of the “Collegio S. Caterina da Siena” of Pavia*.
* “historic” college of Pavia and one of the thirteen Italian university institutions of high cultural qualification set under the control of the Ministry of Education, Universities and Research (MIUR).
Congresses Participation
61st Lindau Nobel Laureate Meeting”. Landau – Germany. 26 june - 2 july 2011.
DGM-IGM Conference. Pavia – Italy. 22-23 February 2011.
“CNR and the New Biology” Conference of the Department of Life Sciences, CNR. Rome - Italy. October 11-12, 2010.
IV Annual EURASNET Meeting. Assisi - Italy. April 23-24, 2009.
EURASNET Interdisciplinary Focus Meeting “Mouse model for alternative splicing”. Assisi - Italy. April 22, 2009.
10th FISV Annual Congress (FISV 2008). Riva del Garda - Italy. September 24-27, 2008.
