Università degli studi di Pavia
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Errichiello's cv
Curriculum
Personal information
Edoardo Errichiello, M.Sc., Clinical Pathologist
E-mail: Edoardo.Errichiello01@universitadipavia.it
Skype: Edoardo.Errichiello
Nationality: Italian
Date of birth: 10-Aug-1983
Work experience
November 2012 – July 2013
Visiting Scientist
Unit of Neurogenetics, National Institute on Aging (NIA), National Institutes of Health (NIH)
Bethesda, MD, US
October 2011 – October 2012
Research Fellow
Unit of Molecular Genetics
Department of Laboratory Medicine, Regina Margherita Children's Hospital
Torino, Italy
April 2011 – September 2011
Visiting Scientist
Unit of Cancer Genomics
Department of Cancer Biology, Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, PA, US
March 2008 – March 2011
Research Fellow
Unit of Stem Cell Transplantation and Cell Therapy, Department of Pediatric Onco-Hematology
Regina Margherita Children's Hospital
Torino, Italy
December 2005 – February 2008
Graduate Student
Unit of Pathology, Institute for Cancer Research and Treatment of Candiolo
Torino, Italy
Education and training
March 2008 – March 2013
Degree “Summa cum laude” in Clinical Pathology
Specialization School in Clinical Pathology
Faculty of Medicine and Surgery
University of Torino, Italy
December 2007
Authorization to pursue the profession of biologist
University of Torino, Italy
September 2005 – October 2007
Degree “Summa cum laude” in Medical Biology (M.Sc.)
Faculty of Mathematics, Physics and Natural Sciences
School of Biological Sciences
University of Torino, Italy
September 2002 – September 2005
Degree “Summa cum laude” in Molecular Biology (B.Sc.)
Faculty of Mathematics, Physics and Natural Sciences
School of Biological Sciences
University of Torino, Italy
Personal skills and competences
Languages
Italian: native speaker
English: advanced
French: basic
Technical skills and competences
Molecular Biology: DNA and RNA extraction from many different biological matrices (blood, buffy coat, saliva, buccal swabs, sputum, formalin fixed paraffin embedded - and frozen tissues, cell culture fluid and cells),DNA/RNA quality check (NanoDrop, Qubit, Agilent 2100 Bioanalyzer), direct sequencing, Next Generation Sequencing (ChiP-seq, RNA-seq, exome sequencing on SOLiD4 and HiSeq 2000), genotyping, Real-Time PCR, Allele Specific-PCR, microsatellite analysis, Southern Blot, Methylation Specific PCR, Competitive Allele Specific PCR (castPCR), pyrosequencing.
Cytogenetics: karyotyping, Fluorescent in situ hibridization (FISH), Flow-FISH.
Cell Biology: cell culture, cell separation, freezing/thawing cells, immunohistochemistry, flow cytometry.
Quality Control: Mycoplasma test, Lymulus Amebocyte Lysate (LAL) test, telomere length analysis.
Haematology: analysis of blood smears, coagulation tests.
Other expertise: Parasitology, Toxicology, urine test, ELISA, HPLC, citological analysis.
Computer skills and competences
Management of bioinformatical and statistical programs.
Experience in using genetic softwares and bioinformatic tools (Gene Mapper, SeqScape, Sequencer, Chrome Lite, BLAST, Primer 3, gPLINK, ...).
Licences
Admission to Italian Association of Biologist, February 2008. N. 059000
Certificate “ABI Prism 3130 and Gene Mapper v4.0”
Certificate “Extraction, Retrotranscription and Application in Real Time PCR”
Certificate “Information Security Awareness” (National Institutes of Health)
Certificate “Privacy Awareness” (National Institutes of Health)
Research Project
Use of Next Generation Sequencing and other whole-genome strategies to dissect neurological diseases
There are several gaps in understanding the many issues related to neurological disorders, considered as one of the greatest threats to public health.
The project is mainly focused on genotype-phenotype relationship in different neurological diseases (such as mental retardation, epilepsy, familial hemiplegic migraine) through different genome-wide approaches, and specifically Whole-Exome Sequencing. Therefore, this work aims to identify novel variants associated with disease and investigate the functional consequences of these mutations.
The project arises from a long-term cooperation between the Unit of Medical Genetics of the University of Pavia and the Fondazione Istituto Neurologico Nazionale C. Mondino.
Publications
Venesio T, Balsamo A, Errichiello E, Ranzani GN, Risio M. Oxidative DNA damage drives carcinogenesis in MUTYH associated polyposis by specific mutations of mitochondrial and MAPK genes. Modern Pathology 2013;26(10):1371-81.
Mereuta OM, Baldovino S, Errichiello E, Binello GB, Restagno G, Battaglia GG, Mazzucco G, Roccatello D. Systemic AA amyloidosis as a unique manifestation of a combined mutation of TNFRSF1A and MEFV genes. Amyloid 2013; 20(2):122-6.
Gunetti M, Tomasi S, Giammò A, Boido M, Rustichelli D, Mareschi K, Errichiello E, Parola M, Ferrero I, Fagioli F, Vercelli A, Carone R. Myogenic potential of whole bone marrow mesenchymal stem cells in vitro and in vivo usage in urinary incontinence. PLoS One 2012;7(9):e45538.
Gunetti M, Noghero A, Molla F, Staszewsky LI, De Angelis N, Soldo A, Russo I, Errichiello E, Frasson C, Rustichelli D, Ferrero I, Gualandris A, Berger M, Geuna M, Scacciatella P, Basso G, marra S, Bussolino F, latini R, Fagioli F.
Ex vivo-expanded bone marrow CD34(+) for acute myocardial infarction treatment: in vitro and in vivo studies. Cytotheraphy 2011;13(9):1140-52.
Abstracts
Purified and expanded BMC for cardiac repair after AMI: preliminary preclinical results. Gunetti M, Ferrero I, Rustichelli D, Errichiello E, Berger M, Fagioli F. 4th Joint Meeting with Mayo Clinic, Torino, 20-21 Novembre 2008.
Le cellule staminali del sangue: vecchi e nuovi protocolli. Ferrero I, Mareschi K, Errichiello E, Rustichelli D, Gunetti M, Sanavio F, Muraro M, Mereuta M, Fagioli F. Convegno Nazionale AIRT (Associazione Interregionale Trapianti) 2009.
Mesenchymal stem cells expansion by plating whole bone marrow at low cellular density: a more advantageous method for clinical use. Mareschi K, Rustichelli D, Gunetti M, Sanavio F, Errichiello E, Ferrero I, Fagioli F. XXVII Conferenza Nazionale di Citometria. Ferrara, 14-17 Ottobre 2009.
Potential and immuno-modulant properties of mesenchymal stem cells from amniotic fluid. Mareschi K, Rustichelli D, Muraro M, Castiglia S, Errichiello E, Signorino E, Fagioli F. 37th Annual Meeting of the European Group for Blood and Marrow Transplantation. Paris, 3-6 Aprile 2011.
Is ALS still a puzzle? A 5-year history. Restagno G, Chiò A, Brunetti M, Ossola I, Barberis M, Errichiello E, Calvo A, Moglia C, Italsgen and Traynor B. Golden Helix Symposia. Torino, 18-21 Aprile 2012.
Somatic mutations in MUTYH-associated polyposis (MAP) syndrome are markers of a defective base-excisione-repair carcinogenesis. Venesio T, Balsamo A, Errichiello E, Ranzani GN, Risio M. Golden Helix Symposia. Torino, 18-21 Aprile 2012.
Genetic analysis in siblings showing the same MUTYH germline genotype but different morphological and clinical phenotypes. Errichiello E, Balsamo A, Fortina P, Ranzani GN, Risio M and Venesio T. AIFEG Congress, Pavia 24-25 Ottobre 2013.
Personal information
Edoardo Errichiello, M.Sc., Clinical Pathologist
E-mail: Edoardo.Errichiello01@universitadipavia.it
Skype: Edoardo.Errichiello
Nationality: Italian
Date of birth: 10-Aug-1983
Work experience
November 2012 – July 2013
Visiting Scientist
Unit of Neurogenetics, National Institute on Aging (NIA), National Institutes of Health (NIH)
Bethesda, MD, US
October 2011 – October 2012
Research Fellow
Unit of Molecular Genetics
Department of Laboratory Medicine, Regina Margherita Children's Hospital
Torino, Italy
April 2011 – September 2011
Visiting Scientist
Unit of Cancer Genomics
Department of Cancer Biology, Kimmel Cancer Center at Thomas Jefferson University
Philadelphia, PA, US
March 2008 – March 2011
Research Fellow
Unit of Stem Cell Transplantation and Cell Therapy, Department of Pediatric Onco-Hematology
Regina Margherita Children's Hospital
Torino, Italy
December 2005 – February 2008
Graduate Student
Unit of Pathology, Institute for Cancer Research and Treatment of Candiolo
Torino, Italy
Education and training
March 2008 – March 2013
Degree “Summa cum laude” in Clinical Pathology
Specialization School in Clinical Pathology
Faculty of Medicine and Surgery
University of Torino, Italy
December 2007
Authorization to pursue the profession of biologist
University of Torino, Italy
September 2005 – October 2007
Degree “Summa cum laude” in Medical Biology (M.Sc.)
Faculty of Mathematics, Physics and Natural Sciences
School of Biological Sciences
University of Torino, Italy
September 2002 – September 2005
Degree “Summa cum laude” in Molecular Biology (B.Sc.)
Faculty of Mathematics, Physics and Natural Sciences
School of Biological Sciences
University of Torino, Italy
Personal skills and competences
Languages
Italian: native speaker
English: advanced
French: basic
Technical skills and competences
Molecular Biology: DNA and RNA extraction from many different biological matrices (blood, buffy coat, saliva, buccal swabs, sputum, formalin fixed paraffin embedded - and frozen tissues, cell culture fluid and cells),DNA/RNA quality check (NanoDrop, Qubit, Agilent 2100 Bioanalyzer), direct sequencing, Next Generation Sequencing (ChiP-seq, RNA-seq, exome sequencing on SOLiD4 and HiSeq 2000), genotyping, Real-Time PCR, Allele Specific-PCR, microsatellite analysis, Southern Blot, Methylation Specific PCR, Competitive Allele Specific PCR (castPCR), pyrosequencing.
Cytogenetics: karyotyping, Fluorescent in situ hibridization (FISH), Flow-FISH.
Cell Biology: cell culture, cell separation, freezing/thawing cells, immunohistochemistry, flow cytometry.
Quality Control: Mycoplasma test, Lymulus Amebocyte Lysate (LAL) test, telomere length analysis.
Haematology: analysis of blood smears, coagulation tests.
Other expertise: Parasitology, Toxicology, urine test, ELISA, HPLC, citological analysis.
Computer skills and competences
Management of bioinformatical and statistical programs.
Experience in using genetic softwares and bioinformatic tools (Gene Mapper, SeqScape, Sequencer, Chrome Lite, BLAST, Primer 3, gPLINK, ...).
Licences
Admission to Italian Association of Biologist, February 2008. N. 059000
Certificate “ABI Prism 3130 and Gene Mapper v4.0”
Certificate “Extraction, Retrotranscription and Application in Real Time PCR”
Certificate “Information Security Awareness” (National Institutes of Health)
Certificate “Privacy Awareness” (National Institutes of Health)
Research Project
Use of Next Generation Sequencing and other whole-genome strategies to dissect neurological diseases
There are several gaps in understanding the many issues related to neurological disorders, considered as one of the greatest threats to public health.
The project is mainly focused on genotype-phenotype relationship in different neurological diseases (such as mental retardation, epilepsy, familial hemiplegic migraine) through different genome-wide approaches, and specifically Whole-Exome Sequencing. Therefore, this work aims to identify novel variants associated with disease and investigate the functional consequences of these mutations.
The project arises from a long-term cooperation between the Unit of Medical Genetics of the University of Pavia and the Fondazione Istituto Neurologico Nazionale C. Mondino.
Publications
Venesio T, Balsamo A, Errichiello E, Ranzani GN, Risio M. Oxidative DNA damage drives carcinogenesis in MUTYH associated polyposis by specific mutations of mitochondrial and MAPK genes. Modern Pathology 2013;26(10):1371-81.
Mereuta OM, Baldovino S, Errichiello E, Binello GB, Restagno G, Battaglia GG, Mazzucco G, Roccatello D. Systemic AA amyloidosis as a unique manifestation of a combined mutation of TNFRSF1A and MEFV genes. Amyloid 2013; 20(2):122-6.
Gunetti M, Tomasi S, Giammò A, Boido M, Rustichelli D, Mareschi K, Errichiello E, Parola M, Ferrero I, Fagioli F, Vercelli A, Carone R. Myogenic potential of whole bone marrow mesenchymal stem cells in vitro and in vivo usage in urinary incontinence. PLoS One 2012;7(9):e45538.
Gunetti M, Noghero A, Molla F, Staszewsky LI, De Angelis N, Soldo A, Russo I, Errichiello E, Frasson C, Rustichelli D, Ferrero I, Gualandris A, Berger M, Geuna M, Scacciatella P, Basso G, marra S, Bussolino F, latini R, Fagioli F.
Ex vivo-expanded bone marrow CD34(+) for acute myocardial infarction treatment: in vitro and in vivo studies. Cytotheraphy 2011;13(9):1140-52.
Abstracts
Purified and expanded BMC for cardiac repair after AMI: preliminary preclinical results. Gunetti M, Ferrero I, Rustichelli D, Errichiello E, Berger M, Fagioli F. 4th Joint Meeting with Mayo Clinic, Torino, 20-21 Novembre 2008.
Le cellule staminali del sangue: vecchi e nuovi protocolli. Ferrero I, Mareschi K, Errichiello E, Rustichelli D, Gunetti M, Sanavio F, Muraro M, Mereuta M, Fagioli F. Convegno Nazionale AIRT (Associazione Interregionale Trapianti) 2009.
Mesenchymal stem cells expansion by plating whole bone marrow at low cellular density: a more advantageous method for clinical use. Mareschi K, Rustichelli D, Gunetti M, Sanavio F, Errichiello E, Ferrero I, Fagioli F. XXVII Conferenza Nazionale di Citometria. Ferrara, 14-17 Ottobre 2009.
Potential and immuno-modulant properties of mesenchymal stem cells from amniotic fluid. Mareschi K, Rustichelli D, Muraro M, Castiglia S, Errichiello E, Signorino E, Fagioli F. 37th Annual Meeting of the European Group for Blood and Marrow Transplantation. Paris, 3-6 Aprile 2011.
Is ALS still a puzzle? A 5-year history. Restagno G, Chiò A, Brunetti M, Ossola I, Barberis M, Errichiello E, Calvo A, Moglia C, Italsgen and Traynor B. Golden Helix Symposia. Torino, 18-21 Aprile 2012.
Somatic mutations in MUTYH-associated polyposis (MAP) syndrome are markers of a defective base-excisione-repair carcinogenesis. Venesio T, Balsamo A, Errichiello E, Ranzani GN, Risio M. Golden Helix Symposia. Torino, 18-21 Aprile 2012.
Genetic analysis in siblings showing the same MUTYH germline genotype but different morphological and clinical phenotypes. Errichiello E, Balsamo A, Fortina P, Ranzani GN, Risio M and Venesio T. AIFEG Congress, Pavia 24-25 Ottobre 2013.
