Universitą degli studi di Pavia
Contenuto della pagina
Sabatini's curriculum
Curriculum vitae
Personal information
Name and surname: Maria Elisa Sabatini
Place and date of birth: Milano (MI) 7th February 1989
Nationality: Italian
e-mail: maeli_89@hotmail.com; mariaelisa.sabatini01@universitadipavia.it
Education
December 2014: Professional qualification as Biologist through State Exam in the Second session of 2014 at the University of Pavia.
November 2012 to the present: Ph.D. student in Genetics, Molecular and Cellular Biology at the Department of Biology and Biotechnology ‘L. Spallanzani’ at University of Pavia, Italy. Ph.D.
2010-2012: Master degree in Molecular Biology and Genetics at the University of Pavia, Italy. Final grade after thesis dissertation: 110/110 cum laude.
2007-2010: Bachelor degree in Biology (address in molecular biology) at the University of Pavia, Italy. Final grade after thesis dissertation: 110/110 cum laude.
2002-2007: High School graduation at Scientific Lyceum ‘A. Einstein’ in Milano, Italy.
Work experience
11-14 February 2015
Visit to Seed Companies in Netherlands (“Seed Valley”). The visit, organized and supported by Eng. Jan Hoopman (Hoopman Group, Aalten) and Dr. Michel Kockelkoren (Agathos, Aalten), was part of the project ‘Primtech-Tecnologie Avanzate di Seed Priming per l’Industria Agro-Sementiera Lombarda’ (scientific coordinator: prof. Alma Balestrazzi).
1st day: visit to the University of Wageningen, seminar of Prof. Steven Groot, international expert in seed physiology; visit to “DEMO” Laboratories of Hoopman Group, Aalten (advanced technologies of “seed coating/drying”, “seed priming/disinfection”), seminars of Eng Jan Hoopman and Dr. Michel Kockelkoren.
2nd day: visit to Bejo Zaden BV (Trambaan), leader company in seed-horticultural branch, scientific discussion with the Dr. Bert Coompan; visit to Plantenkwekerij Gitzels BV, leader company in the horticultural branch.
November 2012 to the present
Research activity concerning Ph.D. student program focused on the characterization of the two plant isoforms of the gene Tyrosyl-DNA phosphodiesterase and the chromatin remodelling in plants. Activity occurred in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
Collaboration activity with Agro Seed Company BEJO ZADEN BV (Netherlands, www.bejo.com; Contact person Dr. Bert Compaan-R&D Department). The project is focused on the application of molecular tools adopted in the Plant Biotechnology Laboratory (Contact person Prof. Alma Balestrazzi) in relation to the seed response to genotoxic stress in samples derived from the germoplasm collection of BEJO ZADEN BV.
March 2012 to July 2012: Stage for Erasmus Placement at the Instituto de Tecnologia Quimica e Biologica (ITQB)- Oeiras- University of Lisbon. Scientific supervisor: Prof. Pedro Fevereiro.
October 2010 to February 2012: Stage for experimental thesis (Master degree) in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
January 2010 to July 2010: Stage for experimental thesis (Bachelor degree) in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
2007-2012: Occasionally employer for Pragma Congressi, Pavia. Hostess activity at scientific congress and events organized by Pragma Congressi enterprise.
Foreign languages
English (good writing, reading and oral expression skills).
Technical skills
PLANT CELL CULTURES
Standard liquid and solid media for in vitro culture of plant cells, tissues and organs.
Standard procedures for in vitro culture of plant cells, tissues and organs (explants sterilization and transfer to in vitro substrates; propagation/maintenance of plant material).
In vitro experience with Medicago truncatula and Petunia hybrida cell suspension and solid cultures.
CELLULAR BIOLOGY
Viability assays with Evans Blue staining (microscopy and spectrophotometric analyses), Trypan Blue and TTC (2,3,5 Triphenyl Tetrazolium Chloride).
Histochemical assays for in situ detection of Reactive Oxygen Species.
Protoplast isolation from plant cell suspension cultures and tissues.
DNA diffusion assay to evaluate cell viability.
Comet assay (Alkalin and Neutral) to evaluate DNA damage in plant cells
Test to evaluate the amount antioxidant compounds in plant tissues: DPPH assay, Folin-Ciocalteu method.
GENE-TRANSFER TECHNIQUES
Construction of recombinant vectors for gene-transfer (conventional, marker-free and cisgenic approach). Agrobacterium tumefaciens-mediated genetic transformation of leaf explants (Medicago truncatula L., Petunia hybrida). In vitro regeneration through somatic embryogenesis. Manipulation and propagation of in vitro grown plantlets.
MOLECULAR BIOLOGY
DNA extraction/purification (plant cell suspensions and tissues, seeds, bacteria, soil) and quantitative analysis (agarose gel electrophoresis, spectrophotometric analysis).
Standard cloning techniques: restriction enzymes, ligation, bacterial transformation (chemical and electroporation), standard PCR analysis, semi-quantitative PCR, RAPDs analysis.
RNA extraction/purification (plant cell suspensions and tissues, seeds, bacteria, soil) and quantitative analysis (agarose gel electrophoresis, spectrophotometric analysis).
cDNA synthesis, qualitative and quantitative evaluation.
Gene expression analysis by QRT-PCR (Quantitative RealTime PCR). Absolute gene transcript quantification by QRT-PCR approach.
Telomere length quantification in plant cells and tissues by QRT-PCR.
COBRA assay for DNA methylation analysis. Methylation-restriction analysis to quantify DNA methylation
BIOINFORMATICS
Standard tools for nucleotide and amino acid sequence analysis (Expasy SIB BLAST Network Service, EMBL-EBI Clustal W2 Multiple Sequence Alignment, Primer3). Databases for gene identification and phylogenetic investigation (Phytozome, Plaza, TAIR, Medicago HapMap). Tools for analysis of DNA consensus sequences in plants (PLACE, PlantCARE).
Other competences
Teaching activity: tutor in the laboratory training of students for the preparation of the experimental Thesis. Supporting activity to Prof. A. Balestrazzi in academic courses. Tutor activity to NASSTEC (NAtive Seed Science, TEchnology and Conservation) PhD students.
Good attitude in group working and interpersonal relationship. Good attitude in the organization of personal and common work in presence of collaboration. Experience in seminar exposition of research activity and in planning activity of experimental thesis.
Research project
Analysis of Tyrosyl-DNA phosphodiesterase isoforms Tdp1α and Tdp1β and role of chromatin remodeling in plants
My research program will be focused on the molecular aspects of the genotoxic stress response in plant cells, the subject currently approached at the laboratory of Plant Biotechnology in the Department of Biology and Biotechnology of the University of Pavia, through new and integrated approaches. Plant organisms are subjected to several environmental abiotic and biotic stresses that determine the accumulation of Reactive Oxygen species (ROS) associated to deleterious effects on the genome stability. Oxidative stress fatally compromises the farm productivity and it’s necessary to define new and effective strategy with the purpose to increase the tolerance to the environmental stresses in the crop fields. New information will be acquired about the role in planta of the Tyrosyl-DNA phosphodiesterase enzymes involved in the NER and BER mechanisms, responsible of DNA repair in different DNA lesions. Functional analysis of the promoters of the genes Mt Tdp1α and Mt Tdp1β, previously isolated and characterized, will be performed through the production of transgenic lines expressing reporter gene construct. Will be so possible verify the spatio-temporal activity of the promoters and explore the possibility for biotechnological applications. In the same time a bioinformatic investigation utilizing data from RNA-seq analysis of Medicago truncatula transgenic lines silenced for the Tdp1α gene will be performed. Considering the relevant role played by the DNA repair processes, the investigation area will be extended to new model systems (ornamental species) and to new problems associated to the damage caused by ionizing radiations.
Publications
Papers
Sabatini ME, Doną M, Leonetti P, Confalonieri M, Minio A, Delledonne M, Giraffa G, Carbonera D, Balestrazzi A. MtTdp1α (Tyrosyl-DNA phosphodiesterase) gene depletion promotes global genome destabilization by affecting chromatin condensation, cytosine methylation, and transposon mobility. Accepted with minor revisions.
Doną M, Sabatini ME, Biggioggera M, Confalonieri M, Minio A, Delledonne M, Giraffa G, Carbonera D, Araujo S, Balestrazzi A. MtTdp1α-depleted Medicago truncatula plants show reduced cuticle permeability and altered expression of defense genes. Submitted for publication.
Carbonera D, Balestrazzi A, Doną M, Macovei A, Sabatini ME, Pagano A. 2015. DNA repair and telomere maintenance during seed imbibition: correlation of transcriptional patterns. Telomere and Telomerase 2: e496
Doną M, Confalonieri M, Minio A, Biggiogera M, Buttafava A, Raimondi E, Delledonne M, Ventura L, Sabatini ME, Macovei A, Giraffa G, Carbonera D, Balestrazzi A. RNA-Seq analysis discloses early senescence and nucleolar dysfunction triggered by TDP1α depletion in Medicago truncatula. Journal of Experimental Botany. Advance Access published March 6, 2013 doi:10.1093/jxb/ert063.
Doną M, Balestrazzi A, Mondoni A, Rossi G, Ventura L, Buttafava A, Macovei A, Sabatini ME, Valassi A, Carbonera D. 2013. DNA profiling, telomere analysis and antioxidant properties as tools for monitoring ex situ seed longevity. Annals of Botany. First published online March 26, 2013 doi:10.1093/aob/mct058.
Abstracts
Sabatini ME, Pagano A, Araujo S, Vandenbussche M, Balestrazzi A, Carbonera D. II International Plant Science Conference (IPSC) “Not only food: sustainable development, agro-biodiversity conservation & human well being”, Pavia (Italia), 14-18 Settembre 2015.
Sabatini ME, Pagano A, Araujo S, Vandenbussche M, Balestrazzi A, Carbonera D. Joint congress SIBV (Societą italiana Biologia Vegetale)-SIGA (Societą Italiana Genetica Agraria) “Feeding the planet: plant science and breeding for the future of agriculture”, Milano (Italia), 8-11 Settembre 2015.
Sabatini ME, Pagano A, Carbonera D, Balestrazzi A. Seed Longevity Workshop of the International Society for Seed Science (ISSS), Wernigerode (Germany), 5-8 Luglio 2015.
Balestrazzi A, Sabatini ME, Fae' M, Paparella S, Carbonera D. 2nd Wg2 And Wg3 Meeting - Cost Action Cm1201 ‘Biomimetic Radical Chemistry’, Antalya (Turkey), 6-9 May 2014.
Balestrazzi A, Giovannini A, Dondi D, Sabatini ME, Carbonera D, Buttafava A. Exploring the molecular and chemical-physical aspects of low-dose irradiation using radio-tolerant plant cells. Radiation Protection Dosimetry. Volume: Proceedings of the 16th International Symposium on Microdosimetry - MICROS 2013, 20-25 October 2013, Treviso Italy
Fač M, Biggiogera M, Sabatini ME, Doną M, Balestrazzi A, Carbonera D. Vth SIBV Congress, Foggia (Italy), 18-20 September 2013.
Doną M, Mondoni A, Rossi G, Abeli T, Sabatini ME, Fač M, Carbonera D, Balestrazzi A. 4th Workshop on the Molecular Aspects of Seed Dormancy and Germination, Paris, (France), 9-12 July 2013.
Giovannini A, Scariot V, Caser M, Buttafava A, Mansuino A, Ghione GG, Sabatini ME, Carbonera D, Balestrazzi A. 4th Workshop on the Molecular Aspects of Seed Dormancy and Germination, Paris (France), 9-12 July 2013,
Sabatini ME, Doną M, Biggiogera M, Carbonera D, Balestrazzi A. SIBBM ‘Frontiers in Molecular Biology’, Pavia (Italy), 5-7 July 2013.
Doną M, Minio A, Biggiogera M, Confalonieri M, Sabatini ME, Raimondi E, Delledonne M, Giraffa G, Carbonera D, Balestrazzi A. RNA-Seq analysis discloses early senescence and nucleolar dysfunction triggered by TDP1α depletion in Medicago truncatula. FISV 2012 Rome (Italy) 24-27 September 2012.
Doną M, Macovei A, Balestrazzi A, Confalonieri M, Sabatini ME, Carbonera D. Characterization of Medicago truncatula TDP1-depleted plants in response to in vitro osmotic stress. 7th International Symposium on in vitro Culture and Horticulture Breeding. Gent (Belgium) 18-22 September 2011.
Macovei A, Doną M, Ventura L, Balestrazzi A, Sabatini ME, Buttafava A, Confalonieri M, Raimondi E, Carbonera D. 2011. Gamma-rays: effects of dose rate on DNA damage, signaling and DNA repair responses in Medicago truncatula cell suspension culture. Structural Biology and DNA repair - A Current Opinion in Structural Biology Conference. Amsterdam (Netherlands) 16-18 October 2011.
Personal information
Name and surname: Maria Elisa Sabatini
Place and date of birth: Milano (MI) 7th February 1989
Nationality: Italian
e-mail: maeli_89@hotmail.com; mariaelisa.sabatini01@universitadipavia.it
Education
December 2014: Professional qualification as Biologist through State Exam in the Second session of 2014 at the University of Pavia.
November 2012 to the present: Ph.D. student in Genetics, Molecular and Cellular Biology at the Department of Biology and Biotechnology ‘L. Spallanzani’ at University of Pavia, Italy. Ph.D.
2010-2012: Master degree in Molecular Biology and Genetics at the University of Pavia, Italy. Final grade after thesis dissertation: 110/110 cum laude.
2007-2010: Bachelor degree in Biology (address in molecular biology) at the University of Pavia, Italy. Final grade after thesis dissertation: 110/110 cum laude.
2002-2007: High School graduation at Scientific Lyceum ‘A. Einstein’ in Milano, Italy.
Work experience
11-14 February 2015
Visit to Seed Companies in Netherlands (“Seed Valley”). The visit, organized and supported by Eng. Jan Hoopman (Hoopman Group, Aalten) and Dr. Michel Kockelkoren (Agathos, Aalten), was part of the project ‘Primtech-Tecnologie Avanzate di Seed Priming per l’Industria Agro-Sementiera Lombarda’ (scientific coordinator: prof. Alma Balestrazzi).
1st day: visit to the University of Wageningen, seminar of Prof. Steven Groot, international expert in seed physiology; visit to “DEMO” Laboratories of Hoopman Group, Aalten (advanced technologies of “seed coating/drying”, “seed priming/disinfection”), seminars of Eng Jan Hoopman and Dr. Michel Kockelkoren.
2nd day: visit to Bejo Zaden BV (Trambaan), leader company in seed-horticultural branch, scientific discussion with the Dr. Bert Coompan; visit to Plantenkwekerij Gitzels BV, leader company in the horticultural branch.
November 2012 to the present
Research activity concerning Ph.D. student program focused on the characterization of the two plant isoforms of the gene Tyrosyl-DNA phosphodiesterase and the chromatin remodelling in plants. Activity occurred in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
Collaboration activity with Agro Seed Company BEJO ZADEN BV (Netherlands, www.bejo.com; Contact person Dr. Bert Compaan-R&D Department). The project is focused on the application of molecular tools adopted in the Plant Biotechnology Laboratory (Contact person Prof. Alma Balestrazzi) in relation to the seed response to genotoxic stress in samples derived from the germoplasm collection of BEJO ZADEN BV.
March 2012 to July 2012: Stage for Erasmus Placement at the Instituto de Tecnologia Quimica e Biologica (ITQB)- Oeiras- University of Lisbon. Scientific supervisor: Prof. Pedro Fevereiro.
October 2010 to February 2012: Stage for experimental thesis (Master degree) in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
January 2010 to July 2010: Stage for experimental thesis (Bachelor degree) in the Plant Biotechnology Laboratory at the Department of Biology and Biotechnology ‘L. Spallanzani’ - University of Pavia. Scientific supervisors: Prof. A. Balestrazzi and Prof. D. Carbonera.
2007-2012: Occasionally employer for Pragma Congressi, Pavia. Hostess activity at scientific congress and events organized by Pragma Congressi enterprise.
Foreign languages
English (good writing, reading and oral expression skills).
Technical skills
PLANT CELL CULTURES
Standard liquid and solid media for in vitro culture of plant cells, tissues and organs.
Standard procedures for in vitro culture of plant cells, tissues and organs (explants sterilization and transfer to in vitro substrates; propagation/maintenance of plant material).
In vitro experience with Medicago truncatula and Petunia hybrida cell suspension and solid cultures.
CELLULAR BIOLOGY
Viability assays with Evans Blue staining (microscopy and spectrophotometric analyses), Trypan Blue and TTC (2,3,5 Triphenyl Tetrazolium Chloride).
Histochemical assays for in situ detection of Reactive Oxygen Species.
Protoplast isolation from plant cell suspension cultures and tissues.
DNA diffusion assay to evaluate cell viability.
Comet assay (Alkalin and Neutral) to evaluate DNA damage in plant cells
Test to evaluate the amount antioxidant compounds in plant tissues: DPPH assay, Folin-Ciocalteu method.
GENE-TRANSFER TECHNIQUES
Construction of recombinant vectors for gene-transfer (conventional, marker-free and cisgenic approach). Agrobacterium tumefaciens-mediated genetic transformation of leaf explants (Medicago truncatula L., Petunia hybrida). In vitro regeneration through somatic embryogenesis. Manipulation and propagation of in vitro grown plantlets.
MOLECULAR BIOLOGY
DNA extraction/purification (plant cell suspensions and tissues, seeds, bacteria, soil) and quantitative analysis (agarose gel electrophoresis, spectrophotometric analysis).
Standard cloning techniques: restriction enzymes, ligation, bacterial transformation (chemical and electroporation), standard PCR analysis, semi-quantitative PCR, RAPDs analysis.
RNA extraction/purification (plant cell suspensions and tissues, seeds, bacteria, soil) and quantitative analysis (agarose gel electrophoresis, spectrophotometric analysis).
cDNA synthesis, qualitative and quantitative evaluation.
Gene expression analysis by QRT-PCR (Quantitative RealTime PCR). Absolute gene transcript quantification by QRT-PCR approach.
Telomere length quantification in plant cells and tissues by QRT-PCR.
COBRA assay for DNA methylation analysis. Methylation-restriction analysis to quantify DNA methylation
BIOINFORMATICS
Standard tools for nucleotide and amino acid sequence analysis (Expasy SIB BLAST Network Service, EMBL-EBI Clustal W2 Multiple Sequence Alignment, Primer3). Databases for gene identification and phylogenetic investigation (Phytozome, Plaza, TAIR, Medicago HapMap). Tools for analysis of DNA consensus sequences in plants (PLACE, PlantCARE).
Other competences
Teaching activity: tutor in the laboratory training of students for the preparation of the experimental Thesis. Supporting activity to Prof. A. Balestrazzi in academic courses. Tutor activity to NASSTEC (NAtive Seed Science, TEchnology and Conservation) PhD students.
Good attitude in group working and interpersonal relationship. Good attitude in the organization of personal and common work in presence of collaboration. Experience in seminar exposition of research activity and in planning activity of experimental thesis.
Research project
Analysis of Tyrosyl-DNA phosphodiesterase isoforms Tdp1α and Tdp1β and role of chromatin remodeling in plants
My research program will be focused on the molecular aspects of the genotoxic stress response in plant cells, the subject currently approached at the laboratory of Plant Biotechnology in the Department of Biology and Biotechnology of the University of Pavia, through new and integrated approaches. Plant organisms are subjected to several environmental abiotic and biotic stresses that determine the accumulation of Reactive Oxygen species (ROS) associated to deleterious effects on the genome stability. Oxidative stress fatally compromises the farm productivity and it’s necessary to define new and effective strategy with the purpose to increase the tolerance to the environmental stresses in the crop fields. New information will be acquired about the role in planta of the Tyrosyl-DNA phosphodiesterase enzymes involved in the NER and BER mechanisms, responsible of DNA repair in different DNA lesions. Functional analysis of the promoters of the genes Mt Tdp1α and Mt Tdp1β, previously isolated and characterized, will be performed through the production of transgenic lines expressing reporter gene construct. Will be so possible verify the spatio-temporal activity of the promoters and explore the possibility for biotechnological applications. In the same time a bioinformatic investigation utilizing data from RNA-seq analysis of Medicago truncatula transgenic lines silenced for the Tdp1α gene will be performed. Considering the relevant role played by the DNA repair processes, the investigation area will be extended to new model systems (ornamental species) and to new problems associated to the damage caused by ionizing radiations.
Publications
Papers
Sabatini ME, Doną M, Leonetti P, Confalonieri M, Minio A, Delledonne M, Giraffa G, Carbonera D, Balestrazzi A. MtTdp1α (Tyrosyl-DNA phosphodiesterase) gene depletion promotes global genome destabilization by affecting chromatin condensation, cytosine methylation, and transposon mobility. Accepted with minor revisions.
Doną M, Sabatini ME, Biggioggera M, Confalonieri M, Minio A, Delledonne M, Giraffa G, Carbonera D, Araujo S, Balestrazzi A. MtTdp1α-depleted Medicago truncatula plants show reduced cuticle permeability and altered expression of defense genes. Submitted for publication.
Carbonera D, Balestrazzi A, Doną M, Macovei A, Sabatini ME, Pagano A. 2015. DNA repair and telomere maintenance during seed imbibition: correlation of transcriptional patterns. Telomere and Telomerase 2: e496
Doną M, Confalonieri M, Minio A, Biggiogera M, Buttafava A, Raimondi E, Delledonne M, Ventura L, Sabatini ME, Macovei A, Giraffa G, Carbonera D, Balestrazzi A. RNA-Seq analysis discloses early senescence and nucleolar dysfunction triggered by TDP1α depletion in Medicago truncatula. Journal of Experimental Botany. Advance Access published March 6, 2013 doi:10.1093/jxb/ert063.
Doną M, Balestrazzi A, Mondoni A, Rossi G, Ventura L, Buttafava A, Macovei A, Sabatini ME, Valassi A, Carbonera D. 2013. DNA profiling, telomere analysis and antioxidant properties as tools for monitoring ex situ seed longevity. Annals of Botany. First published online March 26, 2013 doi:10.1093/aob/mct058.
Abstracts
Sabatini ME, Pagano A, Araujo S, Vandenbussche M, Balestrazzi A, Carbonera D. II International Plant Science Conference (IPSC) “Not only food: sustainable development, agro-biodiversity conservation & human well being”, Pavia (Italia), 14-18 Settembre 2015.
Sabatini ME, Pagano A, Araujo S, Vandenbussche M, Balestrazzi A, Carbonera D. Joint congress SIBV (Societą italiana Biologia Vegetale)-SIGA (Societą Italiana Genetica Agraria) “Feeding the planet: plant science and breeding for the future of agriculture”, Milano (Italia), 8-11 Settembre 2015.
Sabatini ME, Pagano A, Carbonera D, Balestrazzi A. Seed Longevity Workshop of the International Society for Seed Science (ISSS), Wernigerode (Germany), 5-8 Luglio 2015.
Balestrazzi A, Sabatini ME, Fae' M, Paparella S, Carbonera D. 2nd Wg2 And Wg3 Meeting - Cost Action Cm1201 ‘Biomimetic Radical Chemistry’, Antalya (Turkey), 6-9 May 2014.
Balestrazzi A, Giovannini A, Dondi D, Sabatini ME, Carbonera D, Buttafava A. Exploring the molecular and chemical-physical aspects of low-dose irradiation using radio-tolerant plant cells. Radiation Protection Dosimetry. Volume: Proceedings of the 16th International Symposium on Microdosimetry - MICROS 2013, 20-25 October 2013, Treviso Italy
Fač M, Biggiogera M, Sabatini ME, Doną M, Balestrazzi A, Carbonera D. Vth SIBV Congress, Foggia (Italy), 18-20 September 2013.
Doną M, Mondoni A, Rossi G, Abeli T, Sabatini ME, Fač M, Carbonera D, Balestrazzi A. 4th Workshop on the Molecular Aspects of Seed Dormancy and Germination, Paris, (France), 9-12 July 2013.
Giovannini A, Scariot V, Caser M, Buttafava A, Mansuino A, Ghione GG, Sabatini ME, Carbonera D, Balestrazzi A. 4th Workshop on the Molecular Aspects of Seed Dormancy and Germination, Paris (France), 9-12 July 2013,
Sabatini ME, Doną M, Biggiogera M, Carbonera D, Balestrazzi A. SIBBM ‘Frontiers in Molecular Biology’, Pavia (Italy), 5-7 July 2013.
Doną M, Minio A, Biggiogera M, Confalonieri M, Sabatini ME, Raimondi E, Delledonne M, Giraffa G, Carbonera D, Balestrazzi A. RNA-Seq analysis discloses early senescence and nucleolar dysfunction triggered by TDP1α depletion in Medicago truncatula. FISV 2012 Rome (Italy) 24-27 September 2012.
Doną M, Macovei A, Balestrazzi A, Confalonieri M, Sabatini ME, Carbonera D. Characterization of Medicago truncatula TDP1-depleted plants in response to in vitro osmotic stress. 7th International Symposium on in vitro Culture and Horticulture Breeding. Gent (Belgium) 18-22 September 2011.
Macovei A, Doną M, Ventura L, Balestrazzi A, Sabatini ME, Buttafava A, Confalonieri M, Raimondi E, Carbonera D. 2011. Gamma-rays: effects of dose rate on DNA damage, signaling and DNA repair responses in Medicago truncatula cell suspension culture. Structural Biology and DNA repair - A Current Opinion in Structural Biology Conference. Amsterdam (Netherlands) 16-18 October 2011.
