Universitą degli studi di Pavia
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Molinaro research activity
Mutation and expression analysis of CDH1 (E-cadherin) in Hereditary Diffuse Gastric Cancer patients
The aim of my study is to identify CDH1 germline alterations in HDGC families. Several complementary approaches are used (including sequencing, MLPA, RT-PCR, Realtime RT-PCR, SNuPE, MS-PCR, bioinformatic tools) to search for sequence mutations as well as gene deletions and expression defects.
The aim of my study is to identify CDH1 germline alterations in HDGC families. Several complementary approaches are used (including sequencing, MLPA, RT-PCR, Realtime RT-PCR, SNuPE, MS-PCR, bioinformatic tools) to search for sequence mutations as well as gene deletions and expression defects.