Università degli studi di Pavia
Contenuto della pagina
Savio publications
1) L.A. STIVALA, M. SAVIO, O. CAZZALINI, R. PIZZALA, L. REHAK, L. BIANCHI, V. VANNINI, E. PROSPERI
Effect of beta-carotene on cell cycle progression of human fibroblasts.
Carcinogenesis, 17 (11), 2395-2401, 1996.
2) M. SAVIO, L.A. STIVALA, A.I. SCOVASSI, L. BIANCHI, E. PROSPERI
p21waf1/cip1 protein associates with the detergent-insoluble form of PCNA concomitantly with disassembly of PCNA at nucleotide excision repair sites.
Oncogene, 13, 1591-1598, 1996.
3) M. SAVIO, L.A. STIVALA, L. BIANCHI, V. VANNINI, E. PROSPERI
Involvement of the Proliferating Cell Nuclear Antigen (PCNA) in DNA repair induced by alkylating agents and oxidative damage in human fibroblasts.
Carcinogenesis, 19(4) 591-596, 1998.
4) F. ALESSI, S. QUARTA, M. SAVIO, F. RIVA, L. ROSSI, L.A. STIVALA, A.I. SCOVASSI, L. MEIJER, E. PROSPERI
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity.
Experimental Cell Research 245, 8-18, 1998.
5) L.A. STIVALA, M. SAVIO, S. QUARTA, C. SCOTTI, O. CAZZALINI, L. ROSSI, A.I. SCOVASSI, R. PIZZALA, R. MELLI, L. BIANCHI, V. VANNINI, E. PROSPERI
The antiproliferative effect of beta-carotene requires p21 wafl/cipl in normal human fibroblasts.
European Journal of Biochemistry (FEBS journal), 267, 2290-2296, 2000.
6) L.A. STIVALA, M. SAVIO, F. CARAFOLI, P. PERUCCA, L. BIANCHI, G. MAGA, L. FORTI, U.M. PAGNONI, A. ALBINI, E. PROSPERI, V. VANNINI
Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol.
J. Biol. Chem. 276, 22586-22594, 2001.
7) L.A. STIVALA, F. RIVA, O.CAZZALINI, M. SAVIO, E. PROSPERI
p21 (wafl/cipl)-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites.
Oncogene 1;20 (5):563-7D, 2001.
8) A.R. COLLINS, M. DUSINSKA, E.HORVATHOVA, E. MUNRO, M. SAVIO, R. STETINA
Inter-individual differences in repair of DNA base oxidation, measured in vitro with the comet assay. Mutagenesis 16 (4), 297-301, 2001.
9) P. SOMMI, M. SAVIO, L.A. STIVALA, C. SCOTTI, P. MIGNOSI, E. PROSPERI, V. VANNINI, E. SOLCIA
Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression.
Exp. Cell Res. 15;281(1):128-139, 2002.
10) M.C. LAZZE’, R. PIZZALA, M. SAVIO, L.A. STIVALA, E. PROSPERI, L. BIANCHI
Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells.
Mutat. Res. 5;535(1):103-115, 2003.
11) C. SCOTTI, L. IAMELE, A. ALESSANDRINI, V. VANNINI, O.CAZZALINI, M.C. LAZZE’, R. MELLI, M. SAVIO, R. PIZZALA, L.A. STIVALA, S.BIGLIERI, A. TOMASI, L.BIANCHI
Lack of molecular relationships between lipid peroxidation and mitochondrial DNA single strand breaks in isolated rat hepatocytes and mitochondria.
Mitochondrion 2/5: 361-373, 2003.
12) I. FROUIN, G. MAGA, M. DENEGRI, F. RIVA, M. SAVIO, S. SPADARI, E. PROSPERI, I.A. SCOVASSI
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.
J Biol Chem. 278(41): 39265-39268, 2003.
13) F. RIVA, M. SAVIO, O. CAZZALINI, L.A. STIVALA, I.A. SCOVASSI, L.S. COX, B. DUCOMMUN, E. PROSPERI
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.
Exp Cell Res. 293(2):357-367, 2004.
14) M.C. LAZZE’, M. SAVIO, R. PIZZALA, O. CAZZALINI, P. PERUCCA, A.I. SCOVASSI, L.A. STIVALA, E. PROSPERI
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. Carcinogenesis, 25(8):1427-1433, 2004.
15) G.A. LOCATELLI, M. SAVIO, L. FORTI, I. SHEVELEV, K. RAMADAN, L.A. STIVALA, V. VANNINI, U. HUBSCHER, S. SPADARI, G. MAGA
Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.
Biochem J. ,389(pt 2) 259-268, 2005.
16) M.C. LAZZÈ, R. PIZZALA, P. PERUCCA, O. CAZZALINI, M. SAVIO, L. FORTI, V. VANNINI, L. BIANCHI
Anthocyanidins decrease endothelin-1 production and increase endothelial nitric oxide synthase in human endothelial cells.
Molecular Nutrition and Food Research, 50 (1): 44-51, 2006.
17) D. GIULIANI, C. MIONI, D. ALTAVILLA, S. LEONE, C. BAZZANI, L. MINUTOLI, A. BITTO, M.M. CAINAZZO, H. MARINI, D. ZAFFE, A.R. BOTTICELLI, R. PIZZALA, M. SAVIO, D. NECCHI, H.B. SCHIÖTH, A. BERTOLINI, F. SQUADRITO, S. GUARINI
Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.
Endocrinology. 147(3):1126-1135, 2006.
18) M. SAVIO, M. CERRI, O. CAZZALINI, P. PERUCCA, L.A. STIVALA, P. PICHIERRI, A. FRANCHITTO, L. MEIJER, E. PROSPERI
Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.
Cell Cycle, 5 (18): 2153-2159, 2006.
19) P. PERUCCA, O. CAZZALINI, O. MORTUSEWICZ, D. NECCHI, M. SAVIO, T. NARDO, L.A. STIVALA, H. LEONHARDT, M.C. CARDOSO, E. PROSPERI
Spatiotemporal dynamics of p21 CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen.
J. Cell Sci, 119 (Pt 8): 1517-1527, 2006.
20) O. CAZZALINI, P. PERUCCA, M. SAVIO, D. NECCHI, L. BIANCHI, L.A. STIVALA, B. DUCOMMUN, A.I. SCOVASSI, E. PROSPERI
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair.
Nucleic Acid Res., 36 (5): 1713-1722, 2008.
21) F. DONA’, E. PROSPERI, M. SAVIO, T. COPPA, A.I. SCOVASSI, C. MONDELLO
Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.
Int J Oncol, 33(3):613-621, 2008.
22) M. BELLERI, D. RIBATTI, M. SAVIO, L.A. STIVALA, L. FORTI, E. TANGHETTI, P. ALESSI, D. COLTRINI, A. BUGATTI, S. MITOLA, S. NICOLI, V. VANNINI, M. PRESTA
alphavbeta3 Integrin-dependent antiangiogenic activity of resveratrol stereoisomers.
Mol Cancer Ther. 7(12):3761-70, 2008.
23) P. PERUCCA, O. CAZZALINI, M. MADINE, M. SAVIO, R.A. LASKEY, V. VANNINI, E. PROSPERI, L.A. STIVALA.
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence.
Cell Cycle. 8(1):105-114, 2009.
24) M. SAVIO, T. COPPA, O. CAZZALINI, P. PERUCCA, D. NECCHI, T. NARDO, L.A. STIVALA, E. PROSPERI.
Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.
DNA Repair (Amst). 4;8(7):778-785, 2009.
25) M. SAVIO, T. COPPA, L. BIANCHI, V. VANNINI, G. MAGA, L. FORTI, O. CAZZALINI, M.C. LAZZÈ, P. PERUCCA, E. PROSPERI, L.A. STIVALA.
The resveratrol analogue 4,4'-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol.
Int J Biochem Cell Biol. 41(12):2493-2502, 2009.
26) O. CAZZALINI, A.I. SCOVASSI, M. SAVIO, L.A. STIVALA, E. PROSPERI.
Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.
Mutat Res. 704(1-3):12-20, 2010.
27) C. SCOTTI, P. MIGNOSI, P. FILIPAZZI, M.C. LAZZÈ, M. SAVIO, D. CAPPELLETTI, M.V. PASQUETTO, E. SOLCIA, V. VANNINI, P. SOMMI.
Molecular alterations in fibroblasts exposed to Helicobacter pylori broth culture filtrate: a potential trigger of autoimmunity?
Helicobacter. 15(1):76-77, 2010.
28) O. CAZZALINI, F. DONÀ, M. SAVIO, M. TILLHON, C. MACCARIO, P. PERUCCA, L.A. STIVALA, A.I. SCOVASSI, E. PROSPERI.
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.
DNA Repair (Amst). 4;9(6):627-635, 2010.
29) C. SCOTTI, P. SOMMI, M.V. PASQUETTO, D. CAPPELLETTI, S. STIVALA, P. MIGNOSI, M. SAVIO, L.R. CHIARELLI, G. VALENTINI, V.M. BOLANOS-GARCIA, D.S. MERRELL, S. FRANCHINI, M.L. VERONA, C. BOLIS, E. SOLCIA, R. MANCA, D. FRANCIOTTA, A. CASASCO, P. FILIPAZZI, E. ZARDINI, V. VANNINI.
Cell-cycle inhibition by Helicobacter pylori L-asparaginase.
PLoS One. 9;5(11):e13892, 2010.
30) M. SAVIO, D. FERRARO, T. COPPA, P. PERUCCA, O. CAZZALINI, V. VANNINI, E. PROSPERI, L.A. STIVALA
DNA damage and maturation: Analysis with comet BrdU assay in normal and p21-null fibroblasts induced to quiescence.
Mutagenesis pp. 1-28, 2010.
31) T. COPPA, M.C. LAZZE’, O. CAZZALINI, P. PERUCCA, R. PIZZALA, L. BIANCHI, L.A. STIVALA, L. FORTI, C. MACCARIO, V. VANNINI, M. SAVIO.
Structure-activity relationship of resveratrol and its analogue 4,4’-dihydroxy-trans-stilbene toward the endothelin axis in human endothelial cells.
Journal of Medicinal Food 14(10):1173-1180, 2011.
32) C. MACCARIO, M. SAVIO, D. FERRARO, L. BIANCHI, R. PIZZALA, L. PRETALI, L. FORTI, L. A. STIVALA.
The resveratrol analogue 4,4'−dihydroxy−trans−stilbene suppresses transformation in normal mouse fibroblasts and inhibits proliferation and invasion of human breast cancer cells.
Carcinogenesis, 33(11):2172-2180, 2012.
33) L. VENTURA, A. GIOVANNINI, M. SAVIO, M. DONA’, A. MACOVEI, A. BUTTAFAVA, D. CARBONERA, A. BALESTRAZZI.
Single Cell Gel Electrophoresis (Comet) assay with plants: Research on DNA repair and ecogenotoxicity testing.
Chemosphere, 92: 1-9, 2013.
34) M. DONA’, L. VENTURA, A. MACOVEI, M. CONFALONIERI, M. SAVIO, A. GIOVANNINI, D. CARBONERA, A. BALESTRAZZI.
Gamma irradiation with different dose rates induces different DNA damage responses in Petunia x hybrida cells.
Journal of Plant Physiology, 170: 780-787 (2013).
35) F. AREDIA, V. GIANSANTI, G. MAZZINI, M. SAVIO, L.M. ORTIZ, I. JAADANE, N. ZAFFARONI, A. FORLINO, A. TORRIGLIA, A.I. SCOVASSI.
Multiple effects of the Na(+)/H(+) antiporter inhibitor HMA on cancer cells.
Apoptosis, 18 (12): 1586-1598 (2103).
36) L.M. GUAMAN-ORTIZ, M. TILLHON, M. PARKS, I. DUTTO, E. PROSPERI, M. SAVIO, A.G. ARCAMONE, F. BUZZETTI, P. LOMBARDI, A.I. SCOVASSI.
Multiple effects of berberine derivatives on colon cancer cells.
Biomed. Res. Int. 2014: 924585 (2014).
37) P. PERUCCA, M. SAVIO, O. CAZZALINI, R. MOCCHI, C. MACCARIO, S. SOMMATIS, D. FERRARO, R. PIZZALA, L. PRETALI, E. FASANI, A. ALBINI, L.A. STIVALA.
Structure-activity relationship and role of oxygen in the potential antitumour activity of fluoroquinolones in human endothelial cancer cells.
J. Photochem. Photobiol B. 140: 57-68 (2014).
38) J. MORINI, G. BABINI, L. MARIOTTI, G. BAIOCCO, L. NACCI, C. MACCARIO, U. ROβLER, A. MINELLI, M. SAVIO, M. GOMOLKA, U. KULKA, A. OTTOLENGHI, C. DANESINO.
Radiosensitivity in lymphoblastoid cell lines derived from Shwachman-Diamond syndrome patients.
Radiat. Prot. Dosymetry 166 (1-4): 95-100 (2015).
39) M. SAVIO, D. FERRARO, C. MACCARIO, R. VACCARONE, L.D. JENSEN, F. CORANA, B. MANNUCCI, L. BIANCHI, Y. CAO, L.A. STIVALA.
Resveratrol-anlogue 4, 4’-dihydroxy-trans-stilbene potently inhibits cancer invasion and metastasis.
Sci. Rep. 1;6: 19973 (2016).
Effect of beta-carotene on cell cycle progression of human fibroblasts.
Carcinogenesis, 17 (11), 2395-2401, 1996.
2) M. SAVIO, L.A. STIVALA, A.I. SCOVASSI, L. BIANCHI, E. PROSPERI
p21waf1/cip1 protein associates with the detergent-insoluble form of PCNA concomitantly with disassembly of PCNA at nucleotide excision repair sites.
Oncogene, 13, 1591-1598, 1996.
3) M. SAVIO, L.A. STIVALA, L. BIANCHI, V. VANNINI, E. PROSPERI
Involvement of the Proliferating Cell Nuclear Antigen (PCNA) in DNA repair induced by alkylating agents and oxidative damage in human fibroblasts.
Carcinogenesis, 19(4) 591-596, 1998.
4) F. ALESSI, S. QUARTA, M. SAVIO, F. RIVA, L. ROSSI, L.A. STIVALA, A.I. SCOVASSI, L. MEIJER, E. PROSPERI
The cyclin-dependent kinase inhibitors olomoucine and roscovitine arrest human fibroblasts in G1 phase by specific inhibition of CDK2 kinase activity.
Experimental Cell Research 245, 8-18, 1998.
5) L.A. STIVALA, M. SAVIO, S. QUARTA, C. SCOTTI, O. CAZZALINI, L. ROSSI, A.I. SCOVASSI, R. PIZZALA, R. MELLI, L. BIANCHI, V. VANNINI, E. PROSPERI
The antiproliferative effect of beta-carotene requires p21 wafl/cipl in normal human fibroblasts.
European Journal of Biochemistry (FEBS journal), 267, 2290-2296, 2000.
6) L.A. STIVALA, M. SAVIO, F. CARAFOLI, P. PERUCCA, L. BIANCHI, G. MAGA, L. FORTI, U.M. PAGNONI, A. ALBINI, E. PROSPERI, V. VANNINI
Specific structural determinants are responsible for the antioxidant activity and the cell cycle effects of resveratrol.
J. Biol. Chem. 276, 22586-22594, 2001.
7) L.A. STIVALA, F. RIVA, O.CAZZALINI, M. SAVIO, E. PROSPERI
p21 (wafl/cipl)-null human fibroblasts are deficient in nucleotide excision repair downstream the recruitment of PCNA to DNA repair sites.
Oncogene 1;20 (5):563-7D, 2001.
8) A.R. COLLINS, M. DUSINSKA, E.HORVATHOVA, E. MUNRO, M. SAVIO, R. STETINA
Inter-individual differences in repair of DNA base oxidation, measured in vitro with the comet assay. Mutagenesis 16 (4), 297-301, 2001.
9) P. SOMMI, M. SAVIO, L.A. STIVALA, C. SCOTTI, P. MIGNOSI, E. PROSPERI, V. VANNINI, E. SOLCIA
Helicobacter pylori releases a factor(s) inhibiting cell cycle progression of human gastric cell lines by affecting cyclin E/cdk2 kinase activity and Rb protein phosphorylation through enhanced p27(KIP1) protein expression.
Exp. Cell Res. 15;281(1):128-139, 2002.
10) M.C. LAZZE’, R. PIZZALA, M. SAVIO, L.A. STIVALA, E. PROSPERI, L. BIANCHI
Anthocyanins protect against DNA damage induced by tert-butyl-hydroperoxide in rat smooth muscle and hepatoma cells.
Mutat. Res. 5;535(1):103-115, 2003.
11) C. SCOTTI, L. IAMELE, A. ALESSANDRINI, V. VANNINI, O.CAZZALINI, M.C. LAZZE’, R. MELLI, M. SAVIO, R. PIZZALA, L.A. STIVALA, S.BIGLIERI, A. TOMASI, L.BIANCHI
Lack of molecular relationships between lipid peroxidation and mitochondrial DNA single strand breaks in isolated rat hepatocytes and mitochondria.
Mitochondrion 2/5: 361-373, 2003.
12) I. FROUIN, G. MAGA, M. DENEGRI, F. RIVA, M. SAVIO, S. SPADARI, E. PROSPERI, I.A. SCOVASSI
Human proliferating cell nuclear antigen, poly(ADP-ribose) polymerase-1, and p21waf1/cip1. A dynamic exchange of partners.
J Biol Chem. 278(41): 39265-39268, 2003.
13) F. RIVA, M. SAVIO, O. CAZZALINI, L.A. STIVALA, I.A. SCOVASSI, L.S. COX, B. DUCOMMUN, E. PROSPERI
Distinct pools of proliferating cell nuclear antigen associated to DNA replication sites interact with the p125 subunit of DNA polymerase delta or DNA ligase I.
Exp Cell Res. 293(2):357-367, 2004.
14) M.C. LAZZE’, M. SAVIO, R. PIZZALA, O. CAZZALINI, P. PERUCCA, A.I. SCOVASSI, L.A. STIVALA, E. PROSPERI
Anthocyanins induce cell cycle perturbations and apoptosis in different human cell lines. Carcinogenesis, 25(8):1427-1433, 2004.
15) G.A. LOCATELLI, M. SAVIO, L. FORTI, I. SHEVELEV, K. RAMADAN, L.A. STIVALA, V. VANNINI, U. HUBSCHER, S. SPADARI, G. MAGA
Inhibition of mammalian DNA polymerases by resveratrol: mechanism and structural determinants.
Biochem J. ,389(pt 2) 259-268, 2005.
16) M.C. LAZZÈ, R. PIZZALA, P. PERUCCA, O. CAZZALINI, M. SAVIO, L. FORTI, V. VANNINI, L. BIANCHI
Anthocyanidins decrease endothelin-1 production and increase endothelial nitric oxide synthase in human endothelial cells.
Molecular Nutrition and Food Research, 50 (1): 44-51, 2006.
17) D. GIULIANI, C. MIONI, D. ALTAVILLA, S. LEONE, C. BAZZANI, L. MINUTOLI, A. BITTO, M.M. CAINAZZO, H. MARINI, D. ZAFFE, A.R. BOTTICELLI, R. PIZZALA, M. SAVIO, D. NECCHI, H.B. SCHIÖTH, A. BERTOLINI, F. SQUADRITO, S. GUARINI
Both early and delayed treatment with melanocortin 4 receptor-stimulating melanocortins produces neuroprotection in cerebral ischemia.
Endocrinology. 147(3):1126-1135, 2006.
18) M. SAVIO, M. CERRI, O. CAZZALINI, P. PERUCCA, L.A. STIVALA, P. PICHIERRI, A. FRANCHITTO, L. MEIJER, E. PROSPERI
Replication-dependent DNA damage response triggered by roscovitine induces an uncoupling of DNA replication proteins.
Cell Cycle, 5 (18): 2153-2159, 2006.
19) P. PERUCCA, O. CAZZALINI, O. MORTUSEWICZ, D. NECCHI, M. SAVIO, T. NARDO, L.A. STIVALA, H. LEONHARDT, M.C. CARDOSO, E. PROSPERI
Spatiotemporal dynamics of p21 CDKN1A protein recruitment to DNA-damage sites and interaction with proliferating cell nuclear antigen.
J. Cell Sci, 119 (Pt 8): 1517-1527, 2006.
20) O. CAZZALINI, P. PERUCCA, M. SAVIO, D. NECCHI, L. BIANCHI, L.A. STIVALA, B. DUCOMMUN, A.I. SCOVASSI, E. PROSPERI
Interaction of p21(CDKN1A) with PCNA regulates the histone acetyltransferase activity of p300 in nucleotide excision repair.
Nucleic Acid Res., 36 (5): 1713-1722, 2008.
21) F. DONA’, E. PROSPERI, M. SAVIO, T. COPPA, A.I. SCOVASSI, C. MONDELLO
Loss of histone H2AX increases sensitivity of immortalized mouse fibroblasts to the topoisomerase II inhibitor etoposide.
Int J Oncol, 33(3):613-621, 2008.
22) M. BELLERI, D. RIBATTI, M. SAVIO, L.A. STIVALA, L. FORTI, E. TANGHETTI, P. ALESSI, D. COLTRINI, A. BUGATTI, S. MITOLA, S. NICOLI, V. VANNINI, M. PRESTA
alphavbeta3 Integrin-dependent antiangiogenic activity of resveratrol stereoisomers.
Mol Cancer Ther. 7(12):3761-70, 2008.
23) P. PERUCCA, O. CAZZALINI, M. MADINE, M. SAVIO, R.A. LASKEY, V. VANNINI, E. PROSPERI, L.A. STIVALA.
Loss of p21 CDKN1A impairs entry to quiescence and activates a DNA damage response in normal fibroblasts induced to quiescence.
Cell Cycle. 8(1):105-114, 2009.
24) M. SAVIO, T. COPPA, O. CAZZALINI, P. PERUCCA, D. NECCHI, T. NARDO, L.A. STIVALA, E. PROSPERI.
Degradation of p21CDKN1A after DNA damage is independent of type of lesion, and is not required for DNA repair.
DNA Repair (Amst). 4;8(7):778-785, 2009.
25) M. SAVIO, T. COPPA, L. BIANCHI, V. VANNINI, G. MAGA, L. FORTI, O. CAZZALINI, M.C. LAZZÈ, P. PERUCCA, E. PROSPERI, L.A. STIVALA.
The resveratrol analogue 4,4'-dihydroxy-trans-stilbene inhibits cell proliferation with higher efficiency but different mechanism from resveratrol.
Int J Biochem Cell Biol. 41(12):2493-2502, 2009.
26) O. CAZZALINI, A.I. SCOVASSI, M. SAVIO, L.A. STIVALA, E. PROSPERI.
Multiple roles of the cell cycle inhibitor p21(CDKN1A) in the DNA damage response.
Mutat Res. 704(1-3):12-20, 2010.
27) C. SCOTTI, P. MIGNOSI, P. FILIPAZZI, M.C. LAZZÈ, M. SAVIO, D. CAPPELLETTI, M.V. PASQUETTO, E. SOLCIA, V. VANNINI, P. SOMMI.
Molecular alterations in fibroblasts exposed to Helicobacter pylori broth culture filtrate: a potential trigger of autoimmunity?
Helicobacter. 15(1):76-77, 2010.
28) O. CAZZALINI, F. DONÀ, M. SAVIO, M. TILLHON, C. MACCARIO, P. PERUCCA, L.A. STIVALA, A.I. SCOVASSI, E. PROSPERI.
p21CDKN1A participates in base excision repair by regulating the activity of poly(ADP-ribose) polymerase-1.
DNA Repair (Amst). 4;9(6):627-635, 2010.
29) C. SCOTTI, P. SOMMI, M.V. PASQUETTO, D. CAPPELLETTI, S. STIVALA, P. MIGNOSI, M. SAVIO, L.R. CHIARELLI, G. VALENTINI, V.M. BOLANOS-GARCIA, D.S. MERRELL, S. FRANCHINI, M.L. VERONA, C. BOLIS, E. SOLCIA, R. MANCA, D. FRANCIOTTA, A. CASASCO, P. FILIPAZZI, E. ZARDINI, V. VANNINI.
Cell-cycle inhibition by Helicobacter pylori L-asparaginase.
PLoS One. 9;5(11):e13892, 2010.
30) M. SAVIO, D. FERRARO, T. COPPA, P. PERUCCA, O. CAZZALINI, V. VANNINI, E. PROSPERI, L.A. STIVALA
DNA damage and maturation: Analysis with comet BrdU assay in normal and p21-null fibroblasts induced to quiescence.
Mutagenesis pp. 1-28, 2010.
31) T. COPPA, M.C. LAZZE’, O. CAZZALINI, P. PERUCCA, R. PIZZALA, L. BIANCHI, L.A. STIVALA, L. FORTI, C. MACCARIO, V. VANNINI, M. SAVIO.
Structure-activity relationship of resveratrol and its analogue 4,4’-dihydroxy-trans-stilbene toward the endothelin axis in human endothelial cells.
Journal of Medicinal Food 14(10):1173-1180, 2011.
32) C. MACCARIO, M. SAVIO, D. FERRARO, L. BIANCHI, R. PIZZALA, L. PRETALI, L. FORTI, L. A. STIVALA.
The resveratrol analogue 4,4'−dihydroxy−trans−stilbene suppresses transformation in normal mouse fibroblasts and inhibits proliferation and invasion of human breast cancer cells.
Carcinogenesis, 33(11):2172-2180, 2012.
33) L. VENTURA, A. GIOVANNINI, M. SAVIO, M. DONA’, A. MACOVEI, A. BUTTAFAVA, D. CARBONERA, A. BALESTRAZZI.
Single Cell Gel Electrophoresis (Comet) assay with plants: Research on DNA repair and ecogenotoxicity testing.
Chemosphere, 92: 1-9, 2013.
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