Universitą degli studi di Pavia


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Tribioli research activity

Carla Tribioli has extensive experience in the following field: bacterial and yeast genetics, molecular biology, mouse genetics, developmental biology, human genetics, cancer genetics.

Main achievements:
- Construction of linear plasmids autonomously replicating in yeast.
- Cloning of human DNA sequences with the features of origins of replication.
- Isolation and characterization of human genes in Xq28.
- Generation of transgenic mice which develop acute promyelocytic leukemia (APL) and molecular analysis of the mechanisms causing APL.
- Molecular and functional analysis of bone development.
- Generation of Bapx1 knockout mice and characterization of the essential role played by Bapx1 homeobox gene in embryonic development of the axial skeleton and spleen
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