Università degli studi di Pavia


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Orioli pubblicazioni

  1. Murphy C, Orioli D, Lutcke A, Bucci C, Chiariello M, Lehtonen E and Zerial M. (1994) Rab proteins and the regulation of vesicular traffic in polarised cells. In: GTPase-controlled molecular machines. Challenges of Modern Medicine. Corda D, Hamm H, Luini A eds. pp 187-195.
  2. Gassmann M, Casagranda F, Orioli D, Simon H, Lai C, Klein R, and Lemke G. (1995) Aberrant neuronal and cardiac development in mice lacking the ErbB4 neuregulin receptor. Nature 378: 390-394.
  3. Peverali FA, Orioli D, Tonon L, Ciana P, Bunone G, Negri M and Della Valle G. (1996) Retinoic acid-induced growth arrest and differentiation of neuroblastoma cells are counteracted by N-myc and enhanced by max overexpression. Oncogene 12: 457-462.
  4. Henkemeyer M*, Orioli D*, Henderson JT, Saxton TM, Roder J, Pawson T and Klein R. (1996) Nuk controls pathfinding of commissural axons in the mammalian central nervous system. Cell 86: 35-46. *The first two authors equally contributed to this article
  5. Orioli D*, Henkemeyer M*, Lemke G, Klein R and Pawson T. (1996) Sek4 and Nuk receptors cooperate in guidance of commissural axons and in palate formation. EMBO J. 15: 6035-6049. *The first two authors equally contributed to this article
  6. Brambilla R, Bruckner K, Orioli D, Bergemann AD, Flanagan JG and Klein R. (1996) Similarities and differences in the way transmembrane-type ligands interact with the Elk subclass of Eph receptors. Mol. Cell. Neurosc. 8: 199-209.
  7. Orioli D and Klein R. (1997) The Eph receptor family: axonal guidance by contact repulsion. Trends in Genetics 13: 354-359.
  8. Anderson DJ, Barbacid M, Berg LJ, Bergemann AD, Bonhoeffer F, Bohme B, Boyd AW, Brandli AW, Bronner-Fraser M, Caras IW, Cerretti DP, Chambon P, Charnay P, Cheng HJ, Ciossek T, Daar IO, Davis S, Dixit VM, Drescher U, Faissner A, Flanagan JG, Fletcher FA, Fox GM, Frisen J, Gale NW, Gilardi-Hebenstreit P, Goodman CS, Hemmati-Brivanlou A, Henkemeyer M, Hirai H, Holder N, Holland SJ, Hunter T, Ikegaki N, Klein R, Koblar SA, Krull CE, Lansford R, Lemke G, Lindberg RA, Lyman SD, Maisonpierre PC, Marcelle C, Miescher GC, Monschau B, Nicola NA, Nieto MA, Ohta K, O’Leary DDM, Orioli D, Pasquale EB, Pawson T, Reith AD , Rogers J H , Rohrer B M , Sanes J R , Sargent TD , Scales JB , Schindelholz B, Siever DA, Strebhardt K, Sugimura H, Tanaka H, Tang XX, Tessier-Lavigne M, Ullrich A, Valenzuela DM, Verderame MF, Wanaka A, Watt VM, Welcher AA, Wilkinson DG, Winning RS, Yancopoulos GD, Zhou R, Ziemiecki A, Zipursky SL. (1997) Unified Nomenclature for Eph Family Receptors and Their Ligands, The Ephrins. Cell 90: 403-404.
  9. Zacchi P, Stenmark H, Parton RG, Orioli D, Lim F, Giner A, Mellman I, Zerial M and Murphy C. (1998) Rab17 regulates membrane trafficking through apical recycling endosomes in polarized epithelial cells. J. Cell Biol. 140: 1039-1053.
  10. Orioli D*, Colaluca IN, Stefanini M, Riva S, Dotti GC and Peverali AF. (2006) Rac3-induced neuritogenesis requires the binding to Neurabin I. Molecular Biology of the Cell 17: 2391-2400. * corresponding author
  11. D’Errico M, Parlanti E, Teson M, Degan P, Lemma T, Calcagnile A, Iavarone I, Jaruga P, Ropolo M, Pedrini AM, Orioli D, Frosina G, Zambruno G, Dizdaroglu M, Stefanini M and Dogliotti E. (2007) The role of CSA in the response to oxidative DNA damage in human cells. Oncogene 26 (30): 4336-4343.
  12. Paulis M, Bensi M, Orioli D, Mazzini G, D’Incalci M, Falcioni C, Radaelli E, Mondello C, Raimondi E and De Carli L. (2007) Transfer of a human chromosomal vector from a hamster cell line to a mouse embryonic stem cell line. Stem Cell, 10: 2543-2550
  13. Yasuda G, Watanabe E, Nishi R, Mori T, Iwai S, Orioli D, Stefanini M, Hanaoka F and Sugasawa K (2007) In vivo instability and functional defects of XPC protein caused by a pathogenic missense mutation. Mol Cell Biol. 19: 6606-6614.
  14. Botta E, Nardo T, Orioli D, Guglielmino R, Ricotti R, Bondanza S, Benedicenti F, Zambruno G, Stefanini M. (2009) Genotype-phenotype relationships in trichothiodystrophy patients with novel splicing mutations in the XPD gene. Hum Mutat. 30:438-45.
  15. Nardo T, Oneda R, Spivak G, Vaz B, Mortier L, Thomas P, Orioli D, Laugel V, Stary A, Hanawalt PC, Sarasin A, Stefanini M. (2009) A UV-sensitive syndrome patient with a specific CSA mutation reveals separable roles for CSA in response to UV and oxidative DNA damage. Proc Natl Acad Sci USA. 106:6209-14.
  16. Stefanini M, Botta E, Lanzafame M and Orioli D. (2010) Trichothiodystrophy: from basic mechanisms to clinical implications. DNA Repair. 9:2-10.
  17. Orioli D, Compe E, Nardo T, Mura M, Giraudon C, Botta E, Arrigoni L, Peverali FA, Egly JM and Stefanini M (2013) XPD mutations in trichothiodystrophy hamper Collagen VI expression and reveal a role of TFIIH in transcription derepression. Hum Mol Genet. 22:1061-73.
  18. Lanzafame M, Vaz B, Nardo T, Botta E, Orioli D and Stefanini M (2013) From laboratory tests to functional characterisation of Cockayne syndrome. Mech Ageing Dev. 134:171-9.
  19. Arseni L, Lanzafame M, Compe E, Fortugno P, Afonso-Barroso A, Peverali FA, Lehmann AR, Zambruno G, Egly JM, Stefanini M and Orioli D (2015) TFIIH-dependent MMP-1 overexpression in trichothiodystrophy leads to extracellular matrix alterations in patient skin. Proc. Natl. Acad. Sci. 112:1499-504.
  20. Lanzafame M, Botta E, Teson M, Fortugno P, Zambruno G, Stefanini M and Orioli D (2015) Reference Genes for Gene Expression Analysis in Proliferating and Differentiating Human Keratinocytes. Exp Dermatol. 24:314-6
  21. Tintori C, La Sala G, Vignaroli G, Botta L, Fallacara AL, Falchi F, Radi M, Zamperini C, Dreassi E, Dello Iacono L, Orioli D, Biamonti G, Garbelli M, Lossani A, Gasparrini F, Tuccinardi T, Laurenzana I, Angelucci A, Maga G, Schenone S, Brullo C, Musumeci F, Desogus A, Crespan E, Botta M (2015). Studies on the ATP Binding Site of Fyn Kinase for the Identification of New Inhibitors and Their Evaluation as Potential Agents against Tauopathies and Tumors. J. Med. Chem. 58:4590-609.
  22. Kuschal C*, Botta E*, Orioli D*, Digiovanna JJ, Seneca S, Keymolen K, Tamura D, Heller E, Khan SG, Caligiuri G, Lanzafame M, Nardo T, Ricotti R, Peverali FA, Stephens R, Zhao Y, Lehmann AR, Baranello L, Levens D, Kraemer KH, Stefanini M. (2016) GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy. Am J Hum Genet. 98:627-42. *Equal contribution
  23. Pascucci B, D'Errico M, Romagnoli A, De Nuccio C, Savino M, Pietraforte D, Lanzafame M, Calcagnile AS, Fortini P, Baccarini S, Orioli D, Degan P, Visentin S, Stefanini M, Isidoro C, Fimia GM, Dogliotti E. (2016) Overexpression of parkin rescues the defective mitochondrial phenotype and the increased apoptosis of Cockayne Syndrome A cells. Oncotarget ahead of print.
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